[DOWNLOAD] ~ Is There Evidence for a Mortality Difference Between Exogenous Surfactant Preparations in Neonatal RDS? by Journal of Applied Research ~ eBook PDF Kindle ePub Free
eBook details
- Title: Is There Evidence for a Mortality Difference Between Exogenous Surfactant Preparations in Neonatal RDS?
- Author : Journal of Applied Research
- Release Date : January 01, 2008
- Genre: Health & Fitness,Books,Health, Mind & Body,
- Pages : * pages
- Size : 81 KB
Description
ABSTRACT Exogenous surfactants are effective in neonatal respiratory distress syndrome (RDS) because infants born preterm are partially surfactant deficient. While exogenous surfactant has significantly reduced the incidence of RDS-related deaths, no well-conducted, prospective, randomized comparison trial has shown a mortality difference. Claims that some exogenous preparations have shown a mortality benefit rely on 2 studies that were not designed to answer this question. Neither manufacturer of these surfactants has tried to reproduce this important benefit, if real, in rigorous clinical trials of adequate size and power. Based on what we have learned from surfactant research for the past 30 years, claims of differences in mortality for different surfactant preparations must be viewed with extreme caution.
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